Comparison of the outcome of 0.02% mitomycine C versus limbal conjunctival autograft after primary pterygium excision.

Mitomycine C versus Limbal Conjunctival Autograft

Authors

  • Syed Nishat Akram Shalamar Institute of Health Sciences
  • Muhammad Ajmal Chaudhary Sheikh Zayed Medical College, Rahim Yar Khan
  • Muhammad Ajmal Children's Hospital & University of Child Health Sciences, Lahore
  • Nesr Farooq Shalamar Medical & dental College, Lahore

DOI:

https://doi.org/10.61581/MJSP.VOL04/01/04

Keywords:

Limbal conjunctival autograft, Pterygium excision, Mitomycin-c 0.02%, Recurrence

Abstract

Objective: is to compare the outcomes of mitomycin 0.02% intra-operatively and limbal conjunctival autograft after excision of primary pterygium.

Methodology: Randomized controlled trial (RCT) was conducted at Opthalmology department Shalamar medical and Dental College, Lahore from October 2021 to September 2022 in duration of 1 year. A total of 62 patients enrolled in study. Patients were divided into two groups MMC and LCAG. Main variables of study were laterality of pterygium, size of pterygium cross limbus, preoperative and post operative BCVA and proportion of pterygium recurrence in both groups. SPSS version 24 was used for data analysis.

Results: Laterality were right for 48.4% patients in Group MMC and 58.1% for Group LCAG, (p=0.445). The average Size of pterygium cross limbus, Preoperative and postoperative BCVA of both the groups were almost equal, (p>0.050). The recurrences at 3, 6 & 9 months and after 1 year in Group MMC was 12.9%, 6.5%, 16.1%, 9.7%, 45.2% which is greater than Group LCAG 9.7%, 9.7%, 3.2%, 6.5%, 29% respectively, but the difference was statistically insignificant, (p=0.526).

Conclusion: Limbal conjunctival autograft is more successful in prevention of recurrence after excision of primary pterygium as compare intraoperative application of mitomycin-c. But simple excision and LCAG or MMC both are acceptable in terms of minor difference in recurrence rate, surgeon’s skill and preferences of local practice are main risk factors.

 

Author Biographies

  • Syed Nishat Akram, Shalamar Institute of Health Sciences

    Senior Lecturer, Shalamar Medical & Dental College, Lahore

  • Muhammad Ajmal Chaudhary, Sheikh Zayed Medical College, Rahim Yar Khan

    Associate Professor , Paediatric Ophthalmology, Sheikh Zayed medical College, Rahim Yar khan

  • Muhammad Ajmal, Children's Hospital & University of Child Health Sciences, Lahore

    Orthoptist, Children's Hospital & University of Child health Sciences, Lahore

  • Nesr Farooq, Shalamar Medical & dental College, Lahore

    Assistant Professor Ophthalmology, Shalamar medical & Dental College, Lahore

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Published

03-06-2023

Issue

Vol. 4 No. 01 (2023): Medical Journal of South Punjab

Section

Medical Section

License

Copyright (c) 2023 Syed Nishat Akram, Muhammad Ajmal Chaudhary, Muhammad Ajmal, Nesr Farooq

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution (CC-BY) 4.0 License that allows others to share the work with an acknowledgment of the work’s authorship and initial publication in this journal.